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There is already a body of published data on several of these diseases like cystic fibrosis, HIV, emphysema, asthma, cancer, chemotherapy, some allergic disorders, drug toxicity, autism, metabolic disorders, Alzheimers disease, etc, where low levels of glutathione have been found to coexist

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It is also important to point out that unlike Grx1, Grx2 complexes iron (Fe), which is required to modulate its activity (Johansson et al., 2004

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